Introduction to Dynamic Infinity in Oncology: Overcoming Static Mutation Mapping through Adaptive Genomic Frameworks
In this course, learners will be introduced to the concept of Dynamic Infinity in Oncology, a novel approach to tackling the challenge of static mutation mapping with adaptive genomic frameworks. Abstract One of the most significant shifts in the traditional approach to tumor analysis and the new approach of fluid and adaptive models of tumor analysis is one of the most important in the field of personalized oncology in the last few years. The conceptual bedrock of this change is the theory of "Dynamic Infinity" that recognizes the fact that the state space of cancer mutation variability is an essentially infinite and continuously evolving space. Traditional mutation mapping techniques typically use cross-sectional biopsies that are unable to capture the stochastic and highly adaptive nature of tumour microenvironments. This paper begins by briefly discussing the theory of Dynamic Infinity in oncology, followed by a discussion of the methodological shift to real-time genomic...