ENDOCRINOPATHY OR EARLY PUBERYNY: NUTRITIONAL AND CHEMICAL ASSESSMENT OF PACKAGED FOOD PRODUCTS IN CHILDREN
ENDOCRINOPATHY OR EARLY PUBERYNY: NUTRITIONAL AND CHEMICAL ASSESSMENT OF PACKAGED FOOD PRODUCTS IN CHILDREN Abstract The global rise in early puberty in children is an important public health problem, which needs a multi-disciplinary, toxicological, nutritional and computational study. Packaged foods are most common foods consumed by children in today's diet and are a double-edged sword as hyper palatable foods containing excess amounts of sugar and caloric density, and simultaneously containing a hidden vector of exposure to endocrine disrupting chemicals (EDCs) via the synthetic packaging materials. This multi-faceted issue is addressed by a novel, comprehensive method that couples the use of AI-based dietary assessments with quantitative structure activity relationships (QSAR) toxicological modelling and an efficient Bayesian ordinal quantile regression model to dissect complex developmental endpoints. The framework allows for high fidelity exposure information as the packag...